The godfather of House Music Frankie Knuckles has reportedly passed away this week at the age of 59 leaving handfuls of high-profile entertainers shocked and speechless.

According to reports, medical complications ended Knuckles’ life Monday (March 31).

Frankie Knuckles, known in the music biz as the “Godfather of House Music,” passed away suddenly on Monday. He was 59. According to some reports, Knuckles (real name Francis Nicholls) died of complications stemming from Type II Diabetes. Knuckles was inducted into the Dance Music Hall of Fame in 2005 and had a day named after him in Chicago, where he primarily worked in the 1980s. Knuckles won a Grammy in 1997 for Remixer of the Year, Non-Classical. (TMZ)

Atlanta’s DJ Drama immediately reacted to the news via his Twitter page.

“RIP Frankie Knuckles. A true legend.,” Drama wrote April 1. (DJ Drama’s Twitter)

Along with re-tweeting a link to the sad news, ATL’s Lil Jon also paid homage.

“ONE OF MY FAV FRANKIE KNUCKLES JOINTS … #RIPFrankieKnuckles,” Jon tweeted April 1. (Lil Jon’s Twitter)

R&B singer Marsha Ambrosius revealed her emotional reaction early Tuesday morning.

“R.I.P DJ Frankie Knuckles. Prayers to all. This hurts. *heard the news right as I checked into hotel in Chicago.” (Marsha Ambrosius’ Twitter)

Knuckles’ run through the music industry dated back to the 1980’s.

Nobody can agree on who invented the blues or birthed rock & roll, but there is no question that house music came from Frankie Knuckles, who died Monday afternoon of as-yet-undisclosed causes at age 59. One of the Eighties and Nineties’ most prolific house music producers and remixers, Knuckles is, hands down, one of the dozen most important DJs of all time. At his Chicago clubs the Warehouse (1977-82) and Power Plant (1983-85), Knuckles’ marathon sets, typically featuring his own extended edits of a wide selection of tracks from disco to post-punk, R&B to synth-heavy Eurodisco, laid the groundwork for electronic dance music culture–all of it. (Rolling Stone)

Check out Frankie Knuckles’ music: